Make contact with Acrivon

US
  • Watertown, MA, USA
  • 480 Arsenal Way
  • Suite 100
  • Watertown, MA 02472
Scandinavia
  • Lund, Sweden
  • Acrivon AB, Medicon Village, Scheeletorget 1
  • SE-223 81 Lund, Sweden

Careers

Partnership

Press

Interested in covering our scientific advances and patient impact? Make contact at press@acrivon.com.

Current Job Openings

Senior Research Associates

The Role

Acrivon Therapeutics is seeking a highly motivated Senior Research Associate to participate in biomarker discovery and characterization at our location in Watertown, MA. The successful candidate will be engaged in research and development of pharmacodynamic and drug response-predictive biomarkers for our portfolio of oncology drug development programs. The candidate will develop assays for analysis of biomarkers in patient samples from clinical trials and from retrospective cohorts.

Requirements

  • BS/MS in Biological Sciences or in a related discipline
  • At least 3 years of laboratory experience in academic research or industry; experience in cancer research is preferred
  • Experience in biomarker discovery and characterization is a plus
  • Knowledge and experience in immunohistochemistry/immunofluorescence and microscopy is highly desirable
  • Broad molecular biology laboratory skills such as cell-based assays, Western Blot, PCR, etc.
  • Excellent communication, organizational skills and working knowledge of Microsoft Office

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

mshipitsin@acrivon.com

Research Associates

The Role

Acrivon Therapeutics is seeking a highly motivated Research Associate to participate in biomarker discovery and characterization at our location in Watertown, MA. The successful candidate will be engaged in research and development of pharmacodynamic and drug response-predictive biomarkers for our portfolio of oncology drug development programs. The candidate will develop assays for analysis of biomarkers in patient samples from clinical trials and from retrospective cohorts.

Requirements

  • BS/MS in Biological Sciences or in a related discipline
  • 2-3 years of laboratory experience in academic research or industry; experience in cancer research is highly desirable
  • Broad molecular biology laboratory skills such as cell-based assays, microscopy, Western Blot, PCR, etc.
  • Knowledge and experience in immunohistochemistry/immunofluorescence is highly desirable
  • Excellent communication, organizational skills and working knowledge of Microsoft Office.

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

mshipitsin@acrivon.com

Scientist, Translational Cancer Research

The Role

Acrivon Therapeutics is seeking a highly motivated Scientist to join our Translational Biomarker team at our location in Watertown, MA. The successful candidate will be engaged in research and development of pharmacodynamic and drug response-predictive biomarkers and biomarker patient selection tests for our portfolio of clinical and preclinical oncology drug development programs, as well as work closely with the Drug Discovery team to move our therapeutics pipeline forward.

Requirements

  • Ph. D. in Biological Sciences or in a related discipline
  • At least 3 years of postdoctoral laboratory experience in academic research or industry; experience in cancer research is preferred
  • Track record of success in drug and biomarker discovery and translational cancer research
  • Strong proficiency in molecular biology techniques, and diverse cell and protein-based assays and analyses
  • Knowledge and experience in immunohistochemistry/immunofluorescence and microscopy is highly desirable
  • Candidate should demonstrate a high degree of scientific curiosity, independence, responsibility, and commitment, as well as the ability to work effectively in a highly collaborative and focused research environment.
  • Excellent communication, computer and organizational skills

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com

Senior Scientist or Principal Scientist, Translational Cancer Research

The Role

Acrivon Therapeutics is seeking a highly driven and experienced Translational Scientist to join the R&D team at our location in Watertown, MA. The successful candidate will be leading key research projects for the clinical drug and biomarker programs and work closely with the Companion Diagnostic, Clinical and Discovery teams. He/She will be involved in biomarker identification and validation and development of patient selection OncoSignature® tests for one or more of our pipeline programs as part of a team.

Requirements

  • Ph. D. in Biological Sciences or in a related discipline
  • At least 3 years of postdoctoral work and 3+ years of related work experience in pharmaceutical or biotech environment
  • Experience and proven record in leading and/or supporting translational strategy of programs in clinical development in pharmaceutical and/or biotech environment
  • Strong scientific background and achievements in oncology and clinical biomarkers ideally demonstrated by scientific publications and presentations
  • Ability to work efficiently as a team member on multiple programs concurrently and meet timelines
  • Ability to communicate efficiently and build strong relationships with team members across our sites to help foster integration and seamless execution of team objectives.

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com

Director, Program Management

The Role

The Director, Program Management at Acrivon Therapeutics will oversee a wide variety of projects that support all functions. The programs and projects that this role will manage are cross-functional, multi-site, complex and can require overseeing outside vendors and contractors. In this role, the candidate will develop solutions in collaboration with senior leadership, drive strategic projects, internal initiatives, and partner with Business Operations and Finance to develop and drive a budget planning and forecasting process based on aligned program deliverables. The position is on site in Watertown, MA, and will require the individual to interact and build productive working relationships with executive leadership and employees at multiple levels.

Requirements

  • Bachelor’s degree in business, a life sciences discipline, or related field
  • 5+ years project management experience within the biopharma or life sciences industry and/or as a related consultant leading large projects
  • Knowledge and experience in CMC, nonclinical and clinical trial planning and execution
  • Strong written and verbal communication skills.
  • Excellent organization and planning skills.
  • High level of proficiency in MS Office software including Word, Excel, Outlook, Visio, Project and PowerPoint
  • Manages multiple complex cross-functional programs and projects simultaneously
  • Seeks to improve systems, processes, and performance, where applicable.
  • Builds, maintains, and controls project plans highlighting dependencies and the critical path, aligned with corporate goals
  • Organizes and facilitates project team meetings, develops meeting agendas, issues meeting minutes, and tracks action items to completion.
  • Communicates project status, risks, and mitigation plans to appropriate stakeholders to executive leadership.
  • Maintains and logically organizes project related documentation (e.g., timelines, minutes, related documents, etc.) for collaboration

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com

Executive Director or Vice President, Biostatistics

The Role

This position is responsible for all the biostatistical activities at Acrivon Therapeutics, including the development and validation of identified biomarkers and the company´s proprietary OncoSignature® patient selection tests, and will serve as a strategic partner with Clinical Development and Operations, Regulatory Affairs, and our Companion Diagnostics group to help provide statistical expertise and guidance on the design and execution of biomarker and clinical development plans. The successful candidate develops the overall strategy of data acquisition and processing, ensures that appropriate statistical approaches for the design and analysis of clinical studies are employed and ensures the adequate interpretation and presentation of results. The candidate will also have an important role as an internal expert to review and assess biostatistical design and plans developed by external CROs and partners.

Requirements

  • Ph. D. in Biostatistics, Statistics, or closely related discipline with 10+ years of experience or in the pharmaceutical or biotech industry setting
  • Must possess a comprehensive and detailed understanding of statistical experimental design and analysis, clinical trial requirements and statistical software packages such as SAS
  • Strong statistical expertise in univariate and multivariate analyses, logistic regression, Cox regression, and other continuous variable statistical skill sets.
  • Understands regulatory guidelines that affect statistical deliverables
  • Extensive experience with the management and statistical analysis of data obtained from Phase I-III clinical trials or studies
  • Strong interpersonal and effective communication (oral and written) skills
  • Provides sound experimental design and data analysis expertise
  • Authors the protocol statistical sections and generates statistical analysis plans and study randomizations as needed
  • Reviews and signs off on relevant study documents, data management and programming deliverables
  • Manages the CROs performing analysis; interprets study results, and collaborates with medical and biostatistics staff to produce safety monitoring reports, interim and final reports, and publications

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com

Vice President, Companion Diagnostics

The Role

The Vice President of Companion Diagnostics will support Acrivon Therapeutics´ early and late-stage pipeline programs by the successful execution of deliverables in partnership with our external Diagnostics provider through PMA approvals for IVDs. This individual will be accountable for jointly developing biomarker plans that support the clinical and pre-clinical programs, including the strategy and goals, experimental validation, timelines, and budget. This experienced candidate will also drive the evaluation of novel platforms for biomarker identification and companion diagnostic (CDx) development. He/She is expected to have deep scientific, clinical and regulatory expertise in platforms relevant to biomarker development, with demonstrated contributions in support of clinical development programs.

Requirements

  • Doctoral degree (eg, PhD, PharmD) or equivalent experience
  • Minimum of 8-10 years of experience and demonstrated success in biomarker research and development at biotech/pharmaceutical companies; a specific focus on biomarkers, CDx, and translational research is required, ideally including quantitative in situ protein measurements and automated image acquisition platforms
  • Professional knowledge and hands-on scientific expertise and skills in developing and supporting novel biomarker platforms
  • Prior experience with vendor selection and management is expected
  • Experience with the development and support of related SOPs and ICFs is expected
  • Experience with CDx development and knowledge of FDA/CDRH processes and regulations are required
  • Development and implementation of biomarker strategies
  • Support of clinical protocol development
  • KOL & collaborator engagement for biomarker development and translational research studies
  • Develop, track, execute and report on goals and objectives
  • Support budget planning and management

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com

Associate Director or Director, Mass Spectrometry and Proteomics

The Role

Acrivon Therapeutics is hiring a Head of Mass Spectrometry and Proteomics, to join our drug and biomarker discovery team in Lund, Sweden. The successful candidate will bring extensive cutting-edge, hands-on experience in global proteomics and phosphoproteomics analyses, cell signaling and cancer research, and will lead the mass spectrometry activities in close collaboration with our academic co-founder at Copenhagen University and our biology leadership in Lund, Sweden. He/She must thrive in a fast-paced environment with high expectations, as well as be able to put management and leadership skills into practice to establish and run the company´s mass spectrometry site as part of a cross-functional team. He/she will also be expected to draft manuscripts for publications and meeting abstracts based on the company’s phospho-proteomics platform.

Requirements

  • Doctoral degree with post-doctoral experience and at least 5-6 years of academic leadership or biopharma industry experience
  • At least 5 years of demonstrated hands-on experience with mass spectrometry, preferably LC/MS and high-resolution mass spectrometry
  • Experience with phosphoproteomics and core pathway reconstitution and visualization analyses
  • Experience with core analytical techniques and software, including PCA, volcano plots, biological process enrichment, consensus substrate analyses, and other differential analyses
  • Ability to develop and implement methods for high throughput or (semi-)automated data analysis
  • Deep understanding and background in cellular and molecular signaling is preferred
  • Skills to coordinate with external CROs on method development, qualifications, and validations; review and approval SOWs, protocols, and reports
  • Provide mass spectrometry support to scientists in all therapeutic programs at Acrivon

Acrivon Therapeutics is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Acrivon Therapeutics complies with applicable state and local laws governing nondiscrimination in employment.

Please send resume and cover letter to

careers@acrivon.com